Bioactivity Tracing of the Ethanol Extract of Bajakah Tampala (Spatholobus littoralis Hassk.) Typical Plant of Kalimantan Island as Antibiofilm of Staphylococcus aureus

BACKGROUND: Free radicals (oxidants) can cause skin irritation/damage which be a manifestation of minor infections. Not only that, one the complications disease that arise is diabetes mellitus (DM) with diabetic foot ulcers (LKD). LKD very susceptible to exposure microorganisms and develops into infection (DFI). DFI associated presence biofilms in wounds especially those caused by Staphylococcus aureus infection. Bajakah tampala (Spatholobus littoralis hassk) native plants Indonesia has been known have antibacterial activity, while its antibiofilm activity not studied. Evaluation antibiofilms from bajakah plant good novelty value, as well support success treatment infectious. AIM: This study aims determine effectiveness ethanol extract East Kalimantan inhibiting eradicating formation S. biofilms. MATERIALS AND METHODS: The planktonic biofilm inhibition tests were carried out using microtiter broth method. Antibiofilm against was analyzed calculating minimum inhibitor concentration (MBIC50) eradication (MBEC50). In addition, we also additional verification DPPH method inhibitory (IC50) parameter value. RESULTS: results showed 1% gave mid-phase 80.23% w/v ± 0.01, maturation phase 77.23% 0.01 large 75.56% 0.01. test, IC50 value 5.9 ppm strong category. CONCLUSION: Thus, it concluded ethanolic high potential developed candidate for new drugs